Zinc, bromobutyl-
Butylzinc bromide
CAS: 92273-73-9
Molecular Formula: C4H9BrZn
Zinc, bromobutyl- - Names and Identifiers
Zinc, bromobutyl- - Physico-chemical Properties
| Molecular Formula | C4H9BrZn |
| Molar Mass | 202.41 |
| Density | 0.958g/mLat 25°C |
| Flash Point | 1°F |
| Water Solubility | Reacts with water. |
| Exposure Limit | ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)OSHA: TWA 200 ppm(590 mg/m3)NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3) |
| Storage Condition | 2-8°C |
| Sensitive | Air Sensitive |
Zinc, bromobutyl- - Risk and Safety
| Risk Codes | R11 - Highly Flammable R14 - Reacts violently with water R19 - May form explosive peroxides R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R40 - Limited evidence of a carcinogenic effect R36/37 - Irritating to eyes and respiratory system. |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S33 - Take precautionary measures against static discharges. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 3399 4.3/PG 2 |
| WGK Germany | 1 |
| HS Code | 29319090 |
| Hazard Class | 4.3 |
Zinc, bromobutyl- - Introduction
Butylzinc bromide (also known as Butylzinc bromide) is an organic zinc compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: butylzine bromide is a colorless or pale yellow liquid.
-Solubility: Easily soluble in anhydrous solvents, such as ethers and alkanes, soluble in water, but will react violently with water.
-Reactivity: Butylzinc bromide is a strong reducing agent and Lewis base, often used as a reagent for carbon-carbon bond formation in organic synthesis.
Use:
-butylzine bromide is often used as a Grignard reagent in organic synthesis to catalyze coupling reactions (such as Grignard reaction and Solo synthesis) and ring closure reactions.
-It can react with aldehydes, ketones, acyl halides and carboxylic acids and other compounds to form carbon-carbon bonds or carbon-oxygen bonds.
Method:
- Butylzinc bromide can be prepared by reacting butyl lithium or butyl magnesium halide with zinc bromide.
Safety Information:
-butylzine bromide is irritating and corrosive, and has an irritating effect on the skin and eyes.
-Wear appropriate protective clothing and chemical safety glasses when used.
-Avoid inhaling its vapor, it is recommended to use it in a well-ventilated place.
-Store away from fire and oxidant and keep sealed.
Nature:
-Appearance: butylzine bromide is a colorless or pale yellow liquid.
-Solubility: Easily soluble in anhydrous solvents, such as ethers and alkanes, soluble in water, but will react violently with water.
-Reactivity: Butylzinc bromide is a strong reducing agent and Lewis base, often used as a reagent for carbon-carbon bond formation in organic synthesis.
Use:
-butylzine bromide is often used as a Grignard reagent in organic synthesis to catalyze coupling reactions (such as Grignard reaction and Solo synthesis) and ring closure reactions.
-It can react with aldehydes, ketones, acyl halides and carboxylic acids and other compounds to form carbon-carbon bonds or carbon-oxygen bonds.
Method:
- Butylzinc bromide can be prepared by reacting butyl lithium or butyl magnesium halide with zinc bromide.
Safety Information:
-butylzine bromide is irritating and corrosive, and has an irritating effect on the skin and eyes.
-Wear appropriate protective clothing and chemical safety glasses when used.
-Avoid inhaling its vapor, it is recommended to use it in a well-ventilated place.
-Store away from fire and oxidant and keep sealed.
Last Update：2024-04-09 15:18:02
